Promising New Wearable Could Retrain the Brain After StrokeA new and deceptively simple advance in chronic stroke treatment could be a vibrating glove. Researchers at Stanford University and Georgia Tech have developed a wearable device that straps around the wrist and hand, delivering subtle vibrations (akin to a vibrating cellphone) that may relieve spasticity as well as or better than the standard Botox injections. "The vibro-tactile stimulation can be used at home, and we're hoping it can be relatively low cost," said senior study author Allison Okamura, PhD, a mechanical engineer at Stanford University, Stanford, California. For now, the device is available only to clinical trial patients. But the researchers hope to get the glove into — or rather onto — more patients' hands within a few years. A recent grant from the National Science Foundation's Convergence Accelerator program could help pave the way to a commercial product. The team also hopes to expand access in the meantime through larger clinical trials with patients in additional locations. The work builds on accumulating research exploring vibration and other stimulation therapies as treatments for neurological conditions. Other vibrating gloves have helped reduce involuntary movement for patients with Parkinson's. And the University of Kansas Medical Center, Kansas City, Kansas, will soon trial the Food and Drug Administration-approved vagal nerve stimulator, an implantable device intended to treat motor function in stroke survivors. Okamura noted that devices use "different types of vibration patterns and intensities," depending on the disease state they target. Spasticity often develops or worsens months after a stroke. By then, patients may have run out of insurance coverage for rehabilitation. And the effectiveness of Botox injections can "wear out over time," Okamura said. In a clinical trial, patients wore the device for 3 hours a day for 8 weeks, while doing their usual activities. The researchers continued testing their spasticity for 2 more weeks. Symptom relief continued or improved for some patients, even after they stopped using the device. More than half of the participants experienced equal or better results than another group that only received regular Botox injections. |